There are no real difference running a Second life company or a real life one. It is practially the same. I know i have been running small companys for over 30 years. Of cource you have to spend some more time in front of your computer.
If you are serious with your Second life company you should get some kind of website or a blog. You can get further information on your products and connect to the several blog networks that write about Second life. Following up you graphic profile and working on your brand. Second life company is as much work as real life ones and if you need help we are always around.
I spend many hours in front of my computer running 2worlds2go in SL if you want to be successful in your Second life business so have you. But i think i forgot to tell you how much fun it is.
Virtual world artist and blogger. Developer of software and stuff. Read more at My blog
When i am inworld i use my Oculus rift so if i do not answer the chat it is because i cant see my keyboard. Try voice.